Frequently Asked Questions

IVF due dates are generally more accurate than natural pregnancy due dates because the exact fertilization and transfer dates are known. Unlike natural pregnancies that estimate ovulation timing, IVF provides precise dates for:

• Egg retrieval
• Fertilization
• Embryo transfer (day 3 or day 5)

This precision allows for more accurate pregnancy dating and monitoring throughout the pregnancy journey.

For frozen embryo transfer, your due date calculation depends on the embryo’s age at transfer :

• Day 3 embryo transfer: Add 263 days to your transfer date
• Day 5 embryo transfer: Add 261 days to your transfer date

Alternative method: Add 266 days to transfer date, then subtract the embryo’s age (3 or 5 days)

Your first ultrasound after IVF is typically scheduled 3-5 weeks after embryo transfer, which corresponds to 6-7 weeks of pregnancy. This timing allows doctors to:

• Detect fetal heartbeat reliably
• Determine if it’s a single or multiple pregnancy
• Confirm intrauterine pregnancy location
• Assess normal pregnancy development

The ultrasound is usually performed transvaginally for clearer, more accurate images.

The chance of twins with IVF varies but is generally higher than with natural conception :

• Natural pregnancy: About 1.2% chance of twins
• IVF pregnancy: Ranges from 6% to 25% depending on various factors
• Multiple embryo transfer: Significantly increases twin probability
• Single embryo transfer: Reduces twin risk to levels closer to natural conception

Modern practice increasingly favors single embryo transfer to minimize multiple pregnancy risks.

IVF pregnancies typically involve more intensive early monitoring :

• More frequent blood tests: Beta-hCG levels monitored every 48 hours initially
• Earlier ultrasounds: First scan at 6-7 weeks vs. 8-12 weeks for natural pregnancy
• Additional monitoring: May include more frequent check-ups in early pregnancy
• Hormone support: Often requires progesterone supplementation

After the first trimester, monitoring usually follows standard prenatal care protocols.

While IVF due dates are more precise than natural pregnancy dates, slight adjustments may occur after early ultrasounds. However, changes are typically minimal because:

• IVF provides exact fertilization timing
• Early ultrasound measurements can vary slightly
• Most adjustments are within 3-5 days

Your fertility specialist will use both transfer date calculations and ultrasound measurements to determine the most accurate due date.

PICSI యొక్క ప్రధాన ప్రయోజనం, అత్యుత్తమ వీర్యకణాన్ని ఎంచుకునే దాని అధునాతన పద్ధతి. ఈ టెక్నిక్, పరిపక్వ మరియు అపరిపక్వ వీర్యకణాల మధ్య తేడాను గుర్తించడానికి పిండ శాస్త్రవేత్తలకు (Embryologists) వీలు కల్పిస్తుంది. పరిపక్వ వీర్యకణాలు పూర్తిగా అభివృద్ధి చెంది ఉంటాయి మరియు వాటిలో DNA దెబ్బతినే లేదా క్రోమోజోముల సంఖ్యలో లోపాలు ఉండే అవకాశం తక్కువ. అందువల్ల చికిత్సలో వాడటానికి ఇవి ఉత్తమమైనవి.

PICSI, మానవ శరీరంలో సహజంగా ఉండే హైలురోనిక్ యాసిడ్ (HA) అనే పదార్థానికి వీర్యకణాలను గురిచేయడం ద్వారా పనిచేస్తుంది. ఈ ప్రక్రియలో, HAకు అతుక్కోగల సామర్థ్యం ఉన్న వీర్యకణాలను గుర్తిస్తారు, మరియు వాటినే సంతాన చికిత్సలలో ఉపయోగించడానికి ఎంపిక చేస్తారు.

సాధారణ ICSI తో PICSI ని పోలుస్తూ చేసిన పరిశోధనలలో, PICSI తో గణనీయంగా అధిక ఫలదీకరణ రేట్లు సాధించవచ్చని తేలింది. అంతేకాకుండా, దీని ద్వారా ట్రాన్స్‌ఫర్ చేయడానికి అనువైన పిండాల సంఖ్య పెరగడంతో పాటు, అధిక నాణ్యత గల పిండాలు ఎక్కువగా ఉత్పత్తి అవుతాయని కూడా నిరూపించబడింది.

అవును, PICSI పిండం నాణ్యతను గణనీయంగా మెరుగుపరుస్తుంది. పిండం గర్భాశయానికి అతుక్కునే (ఇంప్లాంటేషన్) సామర్థ్యం పెరగడం మరియు అన్యూప్లాయిడీస్ (క్రోమోజోముల సంఖ్యలో ఉండే అసాధారణతలు) ప్రమాదం తగ్గడమే దీనికి నిదర్శనం.

Several factors can influence the uterine environment and embryo health, including hormonal imbalances, underlying medical conditions such as PCOS or endometriosis, uterine anomalies, lifestyle factors like smoking, obesity, or stress, age, exposure to environmental toxins, and genetic or epigenetic influences.

Endometriosis can cause inflammation, scarring, and adhesions in the pelvic region, creating an unfavourable uterine environment. It can alter hormonal levels, restrict blood flow, and potentially obstruct the fallopian tubes or uterine cavity, all of which may impair embryo implantation and development.

The uterine lining, or endometrium, is essential for embryo implantation and nourishment in early pregnancy. If the lining is too thin or not receptive, it can hinder implantation and negatively affect embryo development. Maintaining a healthy, well-prepared endometrial lining is crucial for successful pregnancy.

Uterine fibroids are non-cancerous growths in the uterus that can interfere with fertility by altering the shape and function of the uterine cavity. They may block the fallopian tubes, disrupt implantation, or reduce blood flow to the embryo, ultimately impacting fertility and embryo health.

While there is no evidence that bed rest improves outcomes after embryo transfer, it’s important to relax during the “two-week wait” between the transfer and your official pregnancy test. Gentle activity is generally safe, but avoid intense physical exertion.

Yes, traveling after a blastocyst transfer is generally considered safe. There is no scientific evidence that traveling negatively impacts the success of the embryo transfer. However, it’s always a good idea to avoid stress and stay comfortable during this time.

While no specific activity guarantees implantation, maintaining a balanced and nutritious diet, getting adequate rest, avoiding stress, taking your prescribed medications (especially folic acid), and steering clear of heat exposure and harmful chemicals may help improve the chances of a successful pregnancy.

Some herbal teas contain caffeine or ingredients that may interfere with medications or fertility. It is best to avoid herbal remedies during this time unless recommended by your doctor. Always consult your fertility specialist before using any supplements or herbal products.

Yes, limiting exposure to environmental pollutants and harmful chemicals is important after a blastocyst transfer. These substances can negatively impact implantation and early pregnancy development, so aim to stay in clean, low-stress environments whenever possible.

Honestly? About 60-70% accurate within one week. If you have regular cycles, the LMP method works great. Early ultrasounds are even better. But remember, your baby has their own timeline!

Absolutely! Just use your best average or the conception date if you know it. Your first ultrasound will give you the most accurate dating anyway.

It definitely does! Most calculators (including ours) let you adjust for your actual cycle length. Every woman is different, and that’s perfectly normal.

Here’s a fun fact: only 4 out of 100 babies arrive on their exact due date! About 80% show up within two weeks either way. So think “due season” rather than “due date”.

Right after that positive pregnancy test! You’re probably dying to know anyway. Just remember your doctor might adjust it slightly after your first appointment.

While calculators don’t factor in stress, your overall health matters. Keep taking care of yourself, good nutrition, managing stress, and regular checkups all help.