Frequently Asked Questions
అవును, IVF మందులు ఉష్ణోగ్రత సరళిని గణనీయంగా ప్రభావితం చేస్తాయి:
- స్టిమ్యులేషన్ మందులు: ప్రాథమిక ఉష్ణోగ్రతను పెంచగలవు.
- ప్రొజెస్టెరాన్ సప్లిమెంట్స్: పెరిగిన ఉష్ణోగ్రత అలాగే కొనసాగేలా చేస్తాయి.
- ట్రిగ్గర్ షాట్స్: తాత్కాలికంగా ఉష్ణోగ్రతను పెంచుతాయి.
- సహాయక మందులు: సహజమైన ఉష్ణోగ్రత సరళిని కప్పిపుచ్చవచ్చు.
పిండ బదిలీ తర్వాత ఉష్ణోగ్రతను ట్రాక్ చేయడం సిఫార్సు చేయబడదు, ఎందుకంటే ఇది అనవసరమైన ఒత్తిడికి కారణం కావచ్చు. ఈ దశలో ఉపయోగించే మందులు ఉష్ణోగ్రత సరళిని ప్రభావితం చేస్తాయి, అందువల్ల ఈ రీడింగ్లు చికిత్స విజయాన్ని సూచించే నమ్మదగని సూచికలు.
IVF చికిత్సలో ఉపయోగించే మందులు సహజమైన ఉష్ణోగ్రత సరళిని మారుస్తాయి కాబట్టి, BBT పర్యవేక్షణ ఓవులేషన్ను కచ్చితంగా అంచనా వేయలేదు. అండాల పెరుగుదలను గమనించడానికి మరియు అండాల సేకరణకు సరైన సమయాన్ని నిర్ధారించడానికి డాక్టర్లు రక్త పరీక్షలు మరియు అల్ట్రాసౌండ్ పర్యవేక్షణపై ఆధారపడతారు.
Laser assisted hatching is a technique used in IVF treatment that creates an opening in the zona pellucida (outer shell) of the embryo. The laser beam pulses three times to create a complete gap, allowing embryonic cells to hatch and improve implantation into the uterine lining without affecting the embryo.
Patients over 37 years old, those with frozen embryo replacement (FER), couples who experienced failed IVF/ICSI cycles, poor responders requiring high doses of gonadotropins, those with poor quality embryos, low fertilization rates in previous cycles, and embryos with thick zona pellucida.
Laser assisted hatching is safer than chemical and manual hatching methods, requires fewer embryos to be transferred, increases implantation success rates, reduces chances of multiple pregnancies, and provides better control over opening size compared to mechanical methods using micro-needles.
Unlike chemical hatching which uses Tyrode’s acid and risks chemical exposure to embryos, laser assisted hatching uses an invisible laser beam to dissolve the shell precisely. It eliminates chemical exposure risks and provides exact technique control based on power settings and spot size.
Success depends significantly on the embryologist’s experience and technique execution. The procedure has improved clinical pregnancy rates when performed correctly. The laser technique may vary based on power settings, spot size, and the specific approach used by the experienced embryologist.
Ideal IVF candidates include women with blocked fallopian tubes, endometriosis, PCOS, irregular ovulation cycles, male factor infertility cases, and couples with unexplained infertility. Women with fertility disorders benefit significantly as fertility drugs can induce ovulation and generate healthy eggs.
Women over 37 may experience decreased IVF effectiveness, though age alone doesn’t disqualify all candidates. Those unable to produce healthy eggs may need donor options. Women not interested in using donor eggs when their own aren’t viable may not benefit from IVF.
IVF involves retrieving and fertilizing sperm and egg outside the body, developing them into embryos, then transferring embryos into the woman’s uterus for implantation. The process can use the couple’s own gametes or donor eggs/sperm depending on individual needs.
IVF allows sperm to naturally fertilize eggs in laboratory conditions, while ICSI involves directly injecting a single sperm into an egg. ICSI can improve success chances when male factor infertility is the main challenge, offering better fertilization control.
Yes, couples with unexplained infertility are good IVF candidates. These couples have undergone testing without finding specific fertility issues but struggle with natural conception, fertility medications, or IUI. IVF offers them a viable path to parenthood.
In-vitro maturation (IVM) is a breakthrough fertility treatment using 90% fewer hormones than IVF. Instead of stimulating eggs with heavy hormone doses, IVM retrieves immature eggs and matures them in the laboratory using special proteins like cumin and cAMP modulators.
IVM offers reduced hormone exposure (90% less), costs one-third to half of IVF expenses, fewer medical complications, safer treatment for PCOS patients, less monitoring (1-2 ultrasounds vs 3+ for IVF), and eliminates ovarian hyperstimulation syndrome risks completely.
IVM eliminates the risk of ovarian hyperstimulation syndrome, a serious complication particularly affecting PCOS patients. The significantly reduced hormone requirement makes it ideal for the 10-15% of women with polycystic ovarian syndrome who face higher risks with traditional IVF.
Current IVM limitations include lower efficiency in producing good-quality embryos compared to IVF, and many clinicians preferring IVF for maximizing pregnancy chances. However, improved IVM techniques show 50% increase in embryo numbers and better quality than standard IVM.
The improved IVM treatment is moving into preclinical trial phases. Once approved by regulatory bodies, this advanced fertility treatment could become available to women within 3-5 years, potentially becoming a common alternative to traditional IVF.
Yes, normal delivery is absolutely possible after IVF pregnancy. The mode of delivery depends on factors like mother’s health, baby’s position, pregnancy progress, and underlying conditions. Many IVF women successfully deliver vaginally despite common misconceptions requiring cesarean sections.
Key factors include maternal age, single vs multiple pregnancies, baby’s position, placental health, underlying conditions like hypertension or diabetes, fetal health concerns, and previous C-section history. Advanced maternal age and multiples may increase C-section likelihood.
Benefits include quicker recovery compared to C-section, lower surgical risks and infection rates, emotional satisfaction, immediate mother-baby bonding, enhanced early breastfeeding opportunities, and shorter hospital stays allowing faster return home with the newborn.
Risks include higher chance of preterm labor, increased placental issues like placenta previa or abruption, and potential complications from previous uterine surgeries. However, with advanced medical care and constant monitoring, these risks can be effectively managed.
C-section becomes essential for multiple pregnancies (twins/triplets), breech or transverse baby positions, health complications like preeclampsia or gestational diabetes, and labor complications including prolonged or stalled labor. Safety of mother and baby is always the priority.
Yes, couples can successfully conceive after multiple failures. Mrs. Riya (39) and Mr. Santosh’s case demonstrates that even after 4 failed cycles with low AMH (0.5 ng/mL), pregnancy is possible through optimized treatment protocols and advanced techniques at specialized centers.
Advanced techniques include pre-treatment to improve ovarian response, embryo pooling to increase success chances, Preimplantation Genetic Testing for Aneuploidy (PGTA) for selecting normal embryos, hysteroscopic polypectomy to remove polyps, and natural cycle endometrial preparation for optimal implantation.
