Intrauterine insemination (IUI) is the placing of sperm into a woman’s uterus during ovulation. This procedure is used for couples with unexplained infertility, minimal male factor infertility, and women with cervical mucus problems. IUI is often done in along with ovulation-stimulating drugs. Intrauterine insemination can be performed by using the husband’s sperm or donor sperm. Before Intrauterine insemination, the woman should be evaluated for any hormonal imbalance, infection or any structural problems.

IUI may be used in along with ovulatory medications, such as clomiphene citrate, gonadotropins, or urofollitropin. If injectable ovulation Stimulating drugs are used in an IUI cycle, careful monitoring is essential. Monitoring includes periodic blood tests and ultrasounds beginning around day 6 of the woman’s cycle. Results of these tests will indicate when eggs are mature, prompting the HCG shot.

Intrauterine insemination is also used with specially prepared donor sperm. The sperm bank sends the doctor’s office sperm that is already prepared. Intrauterine insemination is a relatively quick procedure and is performed in the doctor’s office without any anesthesia. It should not be painful, although some women report mild discomfort.

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